课题组组长：沈嘉炜
课题组成员：胡全、郑威、郭勇、沈奇英、魏巧琳、段伟
课题组长简介
沈嘉炜，教授、博士生导师，现任杭州师范大学药学院副院长，中国抗癌协会中西整合控瘤新药研究专业委员会委员，浙江省转化医学会皮肤病学分会常务委员。2004年及2009年在浙江大学化学系获得理学学士和理学博士学位，2009年9月至2013年6月在德国马克斯-普朗克高分子研究所（Max-Planck Institute for Polymer Research）进行博士后研究工作，2013年6月加入杭州师范大学。近年来研究工作集中在生物纳米材料及药物递送材料的计算机模拟、药学递送系统的构建及在抗肿瘤、皮肤病等领域的应用等。目前已主持国家自然科学基金4项，浙江省自然科学基金、浙江省钱江人才项目等纵向、横向课题10余项，主持浙江省一流课程，入选浙江省级人才、杭州市特殊支持创新领军人才等。发表SCI收录论文90余篇，其中以第一作者和通讯作者在Biomaterials、Journal of Controlled Release、Nano Today、Chemical Engineering Journal、Biosensors & Bioelectronics、Journal of Physical Chemistry Letter、Carbohydrate Polymers、Journal of Membrane Science、Journal of Nanobiotechnology、Bioresource Technology等权威SCI期刊发表论文68篇，总被引2600余次。
课题组成员简介
郭勇，男，荷兰乌特勒支大学物理与胶体化学博士，杭州师范大学副教授、硕士生导师，杭州市高层次人才D类，从事生物医用智能材料研发，涉及尿素吸附材料以及智能响应性药物递送材料等领域。迄今以第一作者或通信作者在 J Control Release、Chem Commun、J Colloid Interf Sci、Macromolecules等国际权威期刊发表SCI论文10余篇，主持国家自然科学基金青年项目一项，杭州市高层次留学回国人员在杭创新创业项目一项，校级科研启动金一项。
沈奇英，副教授，现就职于杭州师范大学药学院。2006年6月在浙江大学药学院获得医学硕士学位，同年加入杭州师范大学。近年来主要着力于新型智能响应性纳米递送系统的设计、构建及其在类风湿性关节炎、肿瘤等疾病的应用研究。主持浙江省基础公益研究计划项目、浙江省高等教育“十四五”教学改革项目、浙江省教育厅一般科研项目、浙江省医药卫生科技计划项目、杭州师范大学登峰工程“有组织科研”国家级项目培育专项等多项课题，参与国家自然科学基金、浙江省自然科学基金项目等多项课题。近年来发表SCI收录论文二十余篇，其中以第一作者或通讯作者在Journal of Nanobiotechnology、Biomaterials Advances、International Journal of Pharmaceutics等权威SCI期刊发表论文十余篇。入选杭州市E类人才。指导学生在全国大学生基础医学创新研究大赛国赛中获奖、并获批“国家级大学生创新创业训练项目”、校“星光计划”项目和“本科生创新能力提升工程”项目。
魏巧琳，女，浙江大学医学博士，杭州师范大学副教授、硕士生导师。主要研究方向为响应型仿生纳米生物体系的构建及应用，涉及肿瘤、自身免疫系统疾病、伤口感染等。近五年以第一/通讯作者身份在Adv. Funct. Mater., Adv. Sci., Nano Today, Biomaterials, Mater. Horiz., J. Nanobiotechnol., Acta. Pharm. Sin. B., J. Control. Release等国际知名学术期刊上发表多篇影响因子大于10的论文，累计影响因子超100。主持项目包括：国家自然科学基金青年项目、浙江省自然科学基金探索项目、浙江省医药卫生科技计划项目、杭州师范大学登峰工程“有组织科研”国家级项目培育专项、国家重点实验室开放课题、校级科研启动金等。
段伟，男，浙江大学化学博士。主要研究方向为纳米医药与生物材料，尤其关注皮肤相关疾病（如慢性难愈创面、微生物感染、炎症、浅表肿瘤、附属器再生等）中新型治疗方法的开发。目前在药用功能材料的构建、智能递药系统的设计、生物传感与诊疗技术的开发等领域取得一系列创新性的研究成果，并积极推动其在组织重塑与医美领域的临床应用。近五年以第一/通讯作者身份在Biomaterials, Trends in Anal. Chem., J. Control. Release, Anal. Chem., Biosens. Bioelectron., Acta Biomater., Mater. Today Bio, ACS Appl. Mater. Inter., Environ, Sci. Technol.等国际知名学术期刊上发表学术论文十余篇，论文累计影响因子超100，引用超500次，H因子为15。研究成果被多家学术媒体亮点报道。以主要完成人授权国家发明专利3项，参编Elsevier英文专著1章。目前是硅及先进半导体材料全国重点实验室客座学者，Biomedical Engineering Communications和Biofunctional Materials期刊的青年编委以及多个重要学术期刊的审稿人。主持国家自然科学基金青年项目、浙江省自然科学基金探索项目、浙江省医药卫生科技计划项目、国家重点实验室课题、横向课题等。
团队研究领域：
1. 生物纳米材料及药物递送材料的计算机模拟
2. 药学递送系统的构建及在抗肿瘤、皮肤病和腰椎间盘退变等领域的应用
3. 膜分离材料的多尺度模拟及分子设计
4. 可用于可穿戴人工肾的尿素吸附材料的构建
5. 仿生酶催化与硅基微纳材料
6. 纳米复合凝胶体系的构建及其诊疗一体化应用
团队科研成果：
代表性科研项目
沈嘉炜
1. 壳聚糖作为难溶性抗癌药物递送材料的计算机模拟和分子设计研究、国家自然科学基金面上项目、2024.01-2027.12、主持
2. 石墨烯量子点及其衍生物跨膜传递的分子模拟研究、国家自然科学基金面上项目、2020.01-2023.12、主持
3. 仿生石墨烯纳米孔道中基因传递的多尺度模拟研究、国家自然科学基金面上项目、2017.01-2020.12、主持
4. 多肽与无机晶体相互作用的多尺度模拟方法研究、国家自然科学基金青年项目、2015.01-2017.12、主持
胡全
1. 有序微孔材料制备及其药物负载和控释性能研究、国家自然科学基金面上项目、83万、2015.01-2018.12、主持、结题
2. 核糖核苷酸还原酶与抗肿瘤治疗的研究 省教育厅科研项目2010.01-2012.12、主持、结题
3. 注射用氟氧头孢作用机制与药效研究、浙江省惠迪森药业、10万、2010.01-2012.12、主持、结题
郭勇
1. 可用于可穿戴式人工肾的尿素吸附功能中空纳米球的设计合成及性能研究、国家自然科学基金青年项目、24万、2021.01-2023.12、主持、结题
2. 可用于可穿戴式人工肾的尿素吸附功能中空纳米球的设计合成及性能研究、杭州市高层次留学回国人员在杭创新创业项目、10万、2022.01-2024.12、主持、在研
沈奇英
1. 药学国家一流专业背景下基于科教融合模式的《药剂学》课程教学改革与实践、浙江省高等教育“十四五”教学改革项目、2024.12-2026.11、主持
2. NIR光驱动温敏胶束原位生成Cu(DDC)2增强肿瘤化疗联合化学动力学治疗、浙江省卫生健康科技计划一般项目、2024.01- 2026.12、主持
3. 血管靶向枸橼酸托法替尼温敏脂质体联合微波热疗对类风湿性关节炎的治疗研究、浙江省基础公益研究计划项目、2020.01-2022.12、主持
4. ICAM-1靶向托法替尼温敏胶束联合微波热疗对类风湿性关节炎的治疗研究、浙江省卫生健康科技计划青年创新人才项目、2022.01- 2024.12、主持
5. 温敏脂质体联合微波协同治疗类风湿性关节炎研究、浙江省教育厅一般项目、2019.10-2021.10、主持
魏巧琳
1. 光控释放型表面增强拉曼探针用于乳腺癌精准诊疗可视化及术后协同抗感染研究，国家自然科学基金青年项目，2024.01-2026.12，主持
2. 基于固有免疫激活的响应渗透型金属有机复合纳米体系用于乳腺癌的治疗研究，浙江省自然科学基金探索项目，2023.01-2025.12，主持
3. 拉曼/光声诊疗探针用于乳腺癌精准手术导航联合光热治疗，浙江省医药卫生科技计划项目，2023.01-2025.12，主持
4. 金纳米星/MOF复合纳米体系介导的肿瘤固有免疫激活在乳腺癌光热/免疫协同治疗中的应用，国家重点实验室开放课题，2023.11-2024.11，主持
段伟
1. 限域级联纳米酶的多孔硅基复合诊疗体系用于糖尿病足溃疡创面的一体化护理，国家自然科学基金青年项目，2025.01-2027.12，主持
2. 具有活性氧监控与调控功能的诊疗型非金属纳米酶的构建及其慢性创面联合护理研究，浙江省自然科学基金探索项目，2025.01-2026.12，主持
3. 基于可降解多孔硅载体的智能纳米载药喷雾用于感染烧伤创面联合治疗研究，浙江省医药卫生科技计划项目，2025.01-2027.12，主持
4. 新型智能水凝胶微针贴片用于皮肤感染的药物释放监测和按需治疗，国家重点实验室课题，2025.01-2025.11，主持
5．硅基材料的仿生功能构筑及其在慢性创面修复中的应用，国家重点实验室课题，2025.01-2027.12，主持
代表性论文（第一及通讯作者）：
沈嘉炜
1. Lushuang Xu, Qinyue Chen, Yangwei Qian, Jin Wang, Chenxi Wang, Rui Fan, Jia-Wei Shen*, Qiying Shen*, NIR-activatable proenzyme DSF/CuS@M for synergistic in situ chemotherapy/CDT/PTT/cuproptosis-based antitumor therapy, Chemical Engineering Journal, 2025, 510, 161733.
2. Yangwei Qian, Chenxi Wang, Ruru Xu, Jin Wang, Qinyue Chen, Zirui Zhu, Quan Hu*, Qiying Shen*, Jia-Wei Shen*, Copper-based metal–organic frameworks for antitumor application. Journal of Nanobiotechnology, 2025, 23, 135.
3. Wei Duan, Yue Gao, Ruru Xu, Sheng Huang, Xueqian Xia, Jingwen Zhao, Longhuan Zeng, Qiaolin Wei, Jia-Wei Shen*, Jianmin Wu, Yongke Zheng. Engineering dual-driven pro-angiogenic nanozyme based on porous silicon for synergistic acceleration of burn infected wound healing. Materials Today Bio, 2025, 31, 101522.
4. Xiaorong Yang#, Hong Zhang#, Zehua Wu, Qin Chen, Wei Zheng, Qiying Shen, Qiaolin Wei*, Jia-Wei Shen*, Yong Guo*. Tumor therapy utilizing dual-responsive nanoparticles: A multifaceted approach integrating calcium-overload and PTT/CDT/chemotherapy. Journal of Controlled Release, 2024, 376, 646-658.
5. Yue Li, Zirui Zhu, Shiyuan Hua, Yinghong Wan, Qin Chen, Ge Gao, Hong Zhang, Wei Duan, Wei Zheng, Yong Guo, Quan Hu, Jia-Wei Shen*, Min Zhou*, Qiaolin Wei*. Metal-based nanoparticles promote the activation of cGAS-STING pathway for enhanced cancer immunotherapy. Nano Today, 2024, 58, 102445.
6. Hong Zhang, Xiao Wang, Xiaorong Yang, Zehua Wu, Qin Chen, Qiaolin Wei, Yong Guo*, Quan Hu*, Jia-Wei Shen*. NIR-triggered and Thermoresponsive Core-shell nanoparticles for synergistic anticancer therapy. Journal of Controlled Release, 2024, 374, 194-204.
7. Di Hu, Ruru Xu, Yating Jin, Shuqing Sun, Jing Ye, Jiajia Wu, Zhiyuan Dai, Jia-Wei Shen*, Yanbin Lu*. Green and sustainable extraction of phycocyanin from Spirulina platensis by temperature-sensitive polymer-based aqueous two-phase system and mechanism study. Bioresource Technology, 2024, 407, 131142.
8. Wei Duan, Jingwen Zhao, Yue Gao, Keying Xu, Sheng Huang, Longhuan Zeng, Jia-Wei Shen*, Yongke Zheng*, Jianmin Wu*. Porous silicon-based sensing and delivery platforms for wound management applications. Journal of Controlled Release, 2024, 371, 530-554.
9. Tianyu Li, Jiachen Li, Zhe Kong, Yiran Peng, Jia-Wei Shen*, Li Zhang, Lijun Liang*. Charge govern ion-selective mechanism of YX2 desalination pore using high-throughput computations and machine learning. Desalination, 2024, 584, 117737.
10. X.Y. Liu, X.Y. Liang, J. Yu, K.Y. Xu, J.W. Shen*, Wei Duan*, J.B. Zeng*. Recent development of noble metal-based bimetallic nanoparticles for colorimetric sensing, TrAC-Trends in Analytical Chemistry, 2023, 169, 117386.
11. J.W. Shen*,#, J.C. Li#, J.H. Dai, M.D. Zhou, H. Ren, L. Zhang, Q. Hu, Z. Kong, L.J. Liang*. Molecular dynamics study on the adsorption and release of doxorubicin by chitosan-decorated graphene. Carbohydrate Polymers, 2020, 248, 116809.
12. C. Chen, L.J. Jia, J.C. Li, L. Zhang*, L.J. Liang, E.Y. Chen, Z. Kong, X.P. Wang, W. Zhang, J.W. Shen*. Understanding the effect of hydroxyl/epoxy group on water desalination through lamellar graphene oxide membranes via molecular dynamics simulation. Desalination, 2020, 491, 114560.
13. J.W. Shen*, J.C. Li, F. Liu, L. Zhang*, L.J. Liang, H.B. Wang*. A molecular dynamics study on water desalination using single-layer MoSe2 nanopore. Journal of Membrane Science, 2020, 595, 117611.
14. Z.Y. Xue, Q. Sun, L. Zhang, Z.Z. Kang, L.J. Liang, Q. Wang*, J.W. Shen*. Graphene quantum dot assisted translocation of drugs into a cell membrane, Nanoscale, 2019, 11, 4503-4514.
15. L.J. Liang*, J.W. Shen*, Z.S. Zhang, Q. Wang*. DNA sequencing by two-dimensional materials: As theoretical modeling meets experiments. Biosensors & Bioelectronics, 2017, 89, 280-292.
16. J.W. Shen*, Z. Kong, L. Zhang, L.J. Liang*. Controlled interval of aligned carbon nanotubes arrays for water desalination: A molecular dynamics simulation study. Desalination, 2016, 395, 28-32.
17. J.W. Shen, C.L. Li, N.F.A. van der Vegt, C. Peter*. Understanding the control of mineralization by polyelectrolyte additives: simulation of preferential binding to calcite surfaces. Journal of Physical Chemistry C, 2013, 117, 6904-6913.
18. J.W. Shen, C.L. Li, N.F.A. van der Vegt, C. Peter*. Transferability of coarse grained potentials: implicit solvent models for hydrated ions. Journal of Chemical Theory and Computation, 2011, 7, 1916-1927.
19. J.W. Shen, T. Wu*, Q. Wang*, H.H. Pan. Molecular simulation of protein adsorption and desorption on hydroxyapatite surfaces. Biomaterials, 2008, 29, 513-532. (Leading Opinion Paper, one of 12 figures featured in “2008 - The Year in Images” of Biomaterials)
20. J.W. Shen, T. Wu*, Q. Wang*, Y. Kang. Induced stepwise conformational change of human serum albumin on carbon nanotube surfaces. Biomaterials, 2008, 29, 3847-3855. (one of 12 figures featured in “2008 - The Year in Images” of Biomaterials)
胡全
1. 缪存静，陈俊杰，历星，林鹏程，胡全*，木犀草素逆转由ＴＧＦβ１诱导的人肺癌细胞上皮-间充质转化的实验研究，中国病理生理杂志，2019, 35, 1163-1168.
2. 朱杰晶，金贾力，骆珺婕，许丽华，胡全*，尹洪萍*，Annexin A2 对小鼠脊髓损伤后神经元的保护作用，中国现代应用药学，2015, 32, 1298-1301
3. Q. Hu, J.C. Yu, M. Liu, A.P. Liu, Z.S. Dou, Y Yang*. A low cytotoxic cationic Metal-Organic Framework carrier for controllable drug release. Journal of Medicinal Chemistry, 2014, 57, 5679-5685.
4. Q. Hu, Y.Q. Tan, M. Liu, J.C. Yu, Y.J. Cui, Y. Yang*. A new highly selective and sensitive fluorescent probe for Zn2+ and its application in cell-imaging. Dyes and Pigments, 2014, 107, 45-50.
5. Q. Hu, K.J. Zhang, H.L. Jin, X.A. Chen, M.L. Hu, S. Wang *. Electrochemical investigation on the interaction of benzene sulfonyl 5-fluorouracil derivatives with double-stranded DNA and G-quadruplex DNA. Science China Chemistry, 2012, 55, 1345-1350.
郭勇
1. H. Zhang, X. Wang, X. Yang, Z. Wu, Q. Chen, Q. Wei, Y. Guo*, Q. Hu, J.-W. Shen, NIR-triggered and Thermoresponsive Core-shell nanoparticles for synergistic anticancer therapy. Journal of Controlled Release 2024, 374, 194-204.
2. X. Yang, H. Zhang, Z. Wu, Q. Chen, W. Zheng, Q. Shen, Q. Wei, J.-W. Shen, Y. Guo*, Tumor therapy utilizing dual-responsive nanoparticles: A multifaceted approach integrating calcium-overload and PTT/CDT/chemotherapy. Journal of Controlled Release 2024, 376, 646-658.
3. H. Zhang, X. Yang, Y. Huang, Y. Li, Q. Hu, Q. Wei, W. Xu, W. Ding, Y. Guo*, J.-W. Shen, Reviving Intervertebral Discs: Treating Degeneration Using Advanced Delivery Systems. Molecular Pharmaceutics 2024, 21, 373-392.
4. X.R. Yang, Y. Sun, H. Zhang, F.R. Liu, Q. Chen, Q.Y. Shen, Z. Kong, Q.L. Wei, J.W. Shen, Y. Guo*, CaCO3 nanoplatform for cancer treatment: drug delivery and combination therapy. Nanoscale 2024, 16, 6876-6899.
5. Y.H. Huang, Y.F. Jiang, Y.Y. Mou, M.Y. Li, H. Yu, J.W. Shen, Y. Guo*, Synthesis and urea adsorption capacity of a strong, acidic hollow nanoparticle. Polymer Journal 2024, 56, 553-560.
6. Y. Sun, X. Yang, Z. Wu, Y. Wan, Q. Wei, Q. Hu, Y. Guo*, Additive application for modulating physicochemical properties and antitumor effects of CaCO3 nanodelivery systems. Journal of Drug Delivery Science and Technology 2024, 100, 106080.
7. Y. Huang, H. Zhang, X. Yang, Q. Chen, W. Zheng, J.-W. Shen, Y. Guo*, A review: current urea sorbents for the development of a wearable artificial kidney. Journal of Materials Science 2024, 59, 11669-11686.
8. Y. Guo*, W. K. Kegel, Fabrication of floating colloidal crystal monolayers by convective deposition. Journal of Colloid and Interface Science 2021, 587, 1-13.
9. Y. Guo, B.G.P. van Ravensteijn, and W.K. Kegel*, Dimple Colloids with Tunable Cavity Size and Surface Functionalities. Macromolecules 2019, 52, 4287-4294.
10. Y. Guo, B.G.P. van Ravensteijn, C.H.J. Evers, and W.K. Kegel*, pH Reversible Encapsulation of Oppositely Charged Colloids Mediated by Polyelectrolytes. Langmuir 2017, 33, 4551-4558.
魏巧琳:（ *：corresponding author ；#：co-first author）
1. Y. Li, Z. R. Zhu, S. Y. Hua, Y. H. Wan, Q. Chen, G. Gao, H. Zhang, W. Duan, W. Zheng, Y. Guo, Q. Hu, J. W. Shen*, M. Zhou*, Q. L. Wei*. Metal-based nanoparticles promote the activation of cGAS-STING pathway for enhanced cancer immunotherapy. Nano Today, 2024, 58, 102445. （IF: 14.6）
2. Q. L. Wei, Y. Chen, X. B. Ma, J. F. Ji, Y. Qiao, B. Zhou, F. Ma, D. S. Ling, H. Zhang, M. Tian. J. Tian*, M. Zhou*. High-Efficient Clearable Nanoparticles for Multi-Modal Imaging and Image-Guided Cancer Therapy, Advanced Functional Materials, 2017, 28, 1-12. （IF: 19.6）
3. Q. L. Wei, H. Arami, H. A. Santos, H. B. Zhang, Y. Y. Li, J. He, D. N. Zhong, D. S. Ling*, M. Zhou*. Intraoperative Assessment and Photothermal Ablation of the Tumor Margins Using Gold Nanoparticles, Advanced Science, 2021, 8, 1-15. （IF: 16.3）
4. Q. L. Wei, J. He, S. F. Wang, S. Y. Hua, Y. C. Qi, F. Y. Li, D. S. Ling*, M. Zhou*. Low-dose X-ray enhanced tumor accumulation of theranostic nanoparticles for high-performance bimodal imaging-guided photothermal therapy, Journal of Nanobiotechnology, 2021, 19, 1-17. （IF: 11.4）
5. J. He#, Q. L. Wei# , S. J. Wang, S. Y. Hua, M. Zhou*. Bioinspired protein corona strategy enhanced biocompatibility of Ag-Hybrid hollow Au nanoshells for surface-enhanced Raman scattering imaging and on-demand activation tumor-phototherapy, Biomaterials, 2021, 271: 120734. （IF: 13.1）
6. W. Shao#, Q. L. Wei#, S. F. Wang, F. Y. Li, J. H. Wu, J.F. Ren, F. Y. Cao, H W. Liao, J. Q. Gao, M. Zhou*, D. S. Ling*. Molecular engineering of D–A–D conjugated small molecule nanoparticles for high performance NIR-II photothermal therapy, Materials Horizons, 2020, 7, 1379-1386. （IF: 12.5）
沈奇英
1. Yangwei Qian, Chenxi Wang,, Ruru Xu, Jin Wang, Qinyue Chen, Zirui Zhu, Quan Hu*, Qiying Shen*, and Jia-Wei Shen*. Copper-based meta-organic frameworks for antitumor application. Journal of Nanobiotechnology, 2025, 23: 135.
2. Tingting Liao, Xiaoxiao Chen, Fengkai Qiu, Xinyu Zhang, Fazong Wu, Zhongwei Zhao, Ming Xu, Minjiang Chen, Jia-Wei Shen*, Qiying Shen*, and Jiansong Ji*. Regulation of cancer-associated fbroblasts for enhanced cancer immunotherapy using advanced functional nanomedicines: an updated review. Journal of Nanobiotechnology, 2025, 23: 166.
3. Qiying Shen, Yongzhong Du. A comprehensive review of advanced drug delivery systems for the treatment of rheumatoid arthritis. International Journal of Pharmaceutics, 2023, 635, 122698.
4. Qiying Shen, et al. ICAM-1 targeted thermal-sensitive micelles loaded with tofacitinib for enhanced treatment of rheumatoid arthritis via microwave assistance. Biomaterials Advances, 2022, 138, 212940.
5. Lushuang Xu, Yue Sun, Yue Li, Junli Sun, Yong Guo, Qiying Shen*, Jia-Wei Shen*. Disulfiram: A Food and Drug Administration-approved multifunctional role in synergistically drug delivery systems for tumor treatment. International Journal of Pharmaceutics, 2022, 626, 122130.
6. Qiying Shen, et al. Microwave hyperthermia-responsible flexible liposomal gel as a novel transdermal delivery of methotrexate for enhanced rheumatoid arthritis therapy. Biomaterials Science, 2021, 9(24), 8386-8395.
7. Qiying Shen, et al. Sinomenine hydrochloride loaded thermosensitive liposomes combined with microwave hyperthermia for the treatment of rheumatoid arthritis. International Journal of Pharmaceutics, 2020, 576, 119001.
8. Qiying Shen, et al. Paclitaxel/hydroxypropyl-β-cyclodextrin complexloaded liposomes for overcoming multidrug resistance in cancer chemotherapy. Journal of Liposome Research, 2020, 30(1), 12-20.
段伟（ *：corresponding author ；#：co-first author）
1. Wei Duan, Yue Gao, Ruru Xu, Sheng Huang, Xueqian Xia, Jingwen Zhao, Longhuan Zeng, Qiaolin Wei, Jia-Wei Shen*, Jianmin Wu*, Yongke Zheng*. Engineering dual-driven pro-angiogenic nanozyme based on porous silicon for synergistic acceleration of burn infected wound healing. Materials Today Bio, 2025, 31, 101522
2. Gengchen Guo, Xuqian Ren, Xiang Lia, Xian Wu, Chenxue Qu*, Wei Duan* Jingbin Zeng*. A three-stage amplified pressure bioassay for sensitive detection of cardiac troponin. Talanta, 2025, 289, 127772
3. Wei Duan, Jingwen Zhao, Yue Gao, Keying Xu, Sheng Huang, Jia-Wei Shen*, Yongke Zheng*, Jianmin Wu*. Porous silicon-based sensing and delivery platforms for wound management applications. Journal of Controlled Release, 2024, 371, 530-554
4. Wei Duan*, Keying Xu, Sheng Huang, Yue Gao, Yong Guo, Qiying Shen, Qiaolin Wei, Wei Zheng, Quan Hu*, Jia-Wei Shen*. Nanomaterials-incorporated polymeric microneedles for wound healing applications. International Journal of Pharmaceutics, 2024, 659, 124247
5. Xingyue Liu, Xinyi Liang, Jing Yu, Keying Xu, Jia-Wei Shen, Wei Duan*, Jingbin Zeng*. Recent development of noble metal-based bimetallic nanoparticles for colorimetric sensing. Trends in Analytical Chemistry, 2023, 169, 117386
6. Wei Duan, Jingwen Zhao, Xingyue Liu, Yongke Zheng*, Jianmin Wu*. Trapping and release of NIR-active dye in porous silicon as a theranostic strategy for ROS photothermal monitoring and chronic wound management. Journal of Controlled Release, 2023, 359, 428–440
7. Wei Duan, Jinling Wang, Xiaomeng Peng, Shoufu Cao, Jingjing Shang, Zhiwei Qiu, Xiaoqing Lu, Jingbin Zeng*. Rational design of trimetallic AgPt-Fe3O4 nanozyme for catalyst poisoning-mediated CO colorimetric detection. Biosensors and Bioelectronics, 2023, 223, 115022
8. Wei Duan, Zhiwei Qiu, Shoufu Cao, Qi Guo, Jiankun Huang, Jinyan Xing, Xiaoqing Lu, Jingbin Zeng*. Pd-Fe3O4 Janus nanozyme with rational design for ultrasensitive colorimetric detection of biothiols. Biosensors and Bioelectronics, 2022, 196, 113724
9. Wei Duan, Xingyue Liu, Jingwen Zhao, Xiaoqing Lu, Jianmin Wu*. Porous silicon carrier endowed with photothermal and therapeutic effects for synergistic wound disinfection. ACS Applied Materials & Interfaces, 2022, 14, 43, 48368-48383
10. Wei Duan, Yao Jin, Yaoxuan Cui, Fengna Xi, Xingyue Liu, Fangjie Wo, Jianmin Wu*. A co-delivery platform for synergistic promotion of angiogenesis based on biodegradable, therapeutic and self-reporting luminescent porous silicon microparticles. Biomaterials, 2021, 272, 120772
11. Wei Duan, Ao Liu, Qing Li, Zhiwei Li, Cong-Ying Wen, Zhixiong Cai, Shiming Tang, Xiyou Li and Jingbin Zeng*. Toward ultrasensitive and fast colorimetric detection of indoor formaldehyde across the visible region using cetyltrimethylammonium chloride-capped bone-shaped gold nanorods as “chromophores”. Analyst, 2019, 144, 4582-4588
12. Yaoxuan Cui#, Wei Duan#, Yao Jin, Fangjie Wo, Fengna Xi*, Jianmin Wu*. Graphene quantum dot-decorated luminescent porous silicon dressing for theranostics of diabetic wounds. Acta Biomaterialia, 2021, 131, 544-554
13. Chunpeng Jiao#, Wei Duan#, Xian Wu, Yanxue Shang, Fangdou Zhang, Maosheng Zhang, Xi Chen, Jingbin Zeng*, Chaoyong Yang. Multifunctional nanoprobe amplified ELISA on capillary: a universal platform for simple, rapid and ultrasensitive dual-mode pathogen detection. Analytical Chemistry., 2023, 95, 30, 11316-11325
14. Zhiwei Qiu#, Wei Duan#, Shoufu Cao, Teng Zeng, Tianyu Zhao, Jiankun Huang, Xiaoqing Lu, Jingbin Zeng*. Highly specific colorimetric probe for fluoride by triggering the intrinsic catalytic activity of a AgPt-Fe3O4 hybrid nanozyme encapsulated in SiO2 Shells. Environmental Science & Technology, 2022, 56, 3, 1713-1723
奖项：
沈嘉炜
1. 新型稀缺酶资源研发体系创建及其在医药领域应用、教育部科学技术进步一等奖、2019年1月、16/17
2. 杭州市教育局系统优秀教师、2018年8月
胡全
1. 杭州市131人才第三层次、2011年5月
郭勇
1. 杭州市高层次人才D类、2023年11月
2. 优秀带教教师、2021年6月
3. 毕业论文优秀指导教师、2021年6月
4. 优秀班主任、2023，2024
沈奇英
1. 杭州市高层次人才E类、2022年9月
2. 优秀带教教师，2020年6月
3. 毕业论文优秀指导教师，2020年6月
魏巧琳
1. 杭州市高层次人才E类、2021年1月
2. 优秀带教教师，2022年6月
3. 毕业论文优秀指导教师，2022年6月
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邮箱：shen.jiawei@hotmail.com; shenjiawei@hznu.edu.cn