姓名: 王莹
办公电话：18367124548
邮箱：nancywangying@163.com
指导专业：药理学
课题组网站：
【研究领域】
神经药理学、肿瘤药理学
【主讲课程】
【教育和工作经历】
工作经历
2021.11—至今：浙江大学医学院附属杭州市第一人民医院，院长助理，GCP机构办主任，研究员
2019.01--2021.10：浙江省人民医院临床试验机构办公室，主任；浙江省人民医院I期临床研究中心，负责人
2018.10--2019.03：国家药品监督管理局审核查验中心
2018.01--2018.10：国家卫生健康委科教司规划处
2015.10--2021.10：浙江省人民医院输血科，副研究员
2014.07--2014.10：美国乔治亚州医学院，访问学者
2009.06--2015.09：温州医科大学检验医学院、生命科学学院，助理研究员；学位与研究生工作办公室副主任
2008.06--2009.08：GSK中国研发有限公司，Assistant Scientist
教育经历
2014-2017：博士研究生，同济大学医学院
2006-2008：硕士研究生，浙江大学医学院
2001-2006：本科，浙江大学医学院
【学术简介（限200字）】
浙江省自然科学基金杰出青年基金、浙江省级人才、浙江省卫生高层次创新人才、浙江省151第三层次人才。
以第一完成人获得中国专利奖优秀奖。以第一完成人获得浙江省科学技术进步二等奖1项、浙江省医药卫生科技奖一等奖1项。以主要完成人（前三）获得浙江省科学技术进步二等奖1项，三等奖1项。
近年来相关研究成果以第一或通讯作者在 Redox Biology（2021，2020；IF=11.799）、Theranostics（2021，2021，IF=11.566）、Aging Cell （IF=11.005）、Cell Death Dis.（2021，2021，IF=9.685）、Glia（2020，2016，2013，IF=8.073）、Free Radical Biology and Medicine（IF=8.101）等国际主流学术期刊发表 30余篇 SCI 论文，总影响因子200分以上。
主持国家自然科学基金2项、浙江省自然科学基金等省部级项目6项，主持/参与含973课题等的国家级、省部级课题20余项。已授权5项国家发明专利，10项国家实用新型专利。担任中华医学会等6个国家级学会相关分会的委员，常委。
【主持教学科研项目】省部级以上
主持国家自然科学基金2项、浙江省自然科学基金等省部级项目6项
【代表性论著】
1. Chaoting Zhou, Luyang Wang, Wanye Hu, Lusheng Tang, Ping Zhang, Yan Gao, Jing Du, Yanchun Li, Ying Wang. CDC25C is a prognostic biomarker and correlated with mitochondrial homeostasis in pancreatic adenocarcinoma. Bioengineered. 2022 May;13(5):13089-13107.
2. Haifeng Xu, Bing Xu, Jiayu Hu, Jun Xia, Le Tong, Ping Zhang, Lei Yang, Lusheng Tang, Sufeng Chen, Jing Du, Ying Wang, Yanchun Li. Development of a novel autophagy-related gene model for gastric cancer prognostic prediction. Front Oncol. 2022 Oct 7;12:1006278.
3. Xingxing Xu#, Jiaojiao Wang#, Siyu Du#, Xiya Shen, Jiashu Lian, Jian Zhou, Mianxian Wang, Wenjin Feng, Zhaoting Lv, Lingting Jin, Huankun Sun, Lihao Wu, Xiaoning Wang, Haoyu Qiu, Junzhe Zhu, Wei Wang, Honglin Teng*, Zhihui Huang*.YAP regulates glutamate homeostasis through promoting the expression of EAAT2 in astrocytes via β-catenin signaling, Glia, in press, 2023. (通讯作者, SCI, IF=8.073).
4. Yanchun Li, Bing Xu, Xueying Ren, Luyang Wang, Yaqing Xu, Yefeng Zhao, Chen Yang, Chen Yuan, Huanjuan Li, Xiangmin Tong, Ying Wang*, Jing Du. Inhibition of CISD2 promotes ferroptosis through ferritinophagy-mediated ferritin turnover and regulation of p62-Keap1-NRF2 pathway. Cell Mol Biol Lett. 2022 Sep 30;27(1):81. (通讯作者, SCI, IF=8.702)
5. Lingting Jin, Jingjing Zhang, Xin Hua, Xingxing Xu, Jia Li, Jiaojiao Wang, Mianxian Wang, Huitao Liu, Haoyu Qiu, Man Chen, Xu Zhang, Ying Wang*, Zhihui Huang. Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling. Cell Death Dis. 2022 Sep 2;13(9):759. (通讯作者, SCI, IF=9.685)
6. Xingxing Xu, Ying Wang, Zhihui Huang. YAP: a novel target for Alzheimer's disease. Aging (Albany NY). 2022 Apr 28;14(9):3724-3725. (第二作者, SCI, IF=5.955)
7. Haoran Li, Bing Xu, Jing Du, Yunyi Wu, Fangchun Shao, Yan Gao, Ping Zhang, Junyu Zhou, Xiangmin Tong, Ying Wang*, Yanchun Li. Autophagy-related prognostic signature characterizes tumor microenvironment and predicts response to ferroptosis in gastric cancer. Front Oncol. 2022 Aug 16;12:959337. (通讯作者, SCI, IF=5.738)
8. Luyang Wang, Hairui Wang, Chen Yang, Yunyi Wu, Guojie Lei, Yanhua Yu, Yan Gao, Jing Du, Xiangmin Tong, Feifei Zhou, Yanchun Li, Ying Wang*. Investigating CENPW as a Novel Biomarker Correlated With the Development and Poor Prognosis of Breast Carcinoma. Front Genet. 2022 Jun 17;13:900111. (通讯作者, SCI, IF=4.772)
9. Yang J, Zhou Y, Li Y, Hu W, Yuan C, Chen S, Ye G, Chen Y, Wu Y, Liu J, Wang Y*, Du J, Tong X. Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis. Bioengineered. 2022 Apr;13(4):11187-11207. (通讯作者, SCI, IF=6.832)
10. Wu Q, Xu X, Miao X, Bao X, Li X, Xiang L, Wang W, Du S, Lu Y, Wang X, Yang D, Zhang J, Shen X, Li F, Lu S, Fan Y, Xu S, Chen Z, Wang Y*, Teng H, Huang Z. YAP signaling in horizontal basal cells promotes the regeneration of olfactory epithelium after injury. Stem Cell Reports. 2022 Mar 8;17(3):664-677. (通讯作者, SCI, IF=7.294)
11. Chen Yang, Yanchun Li, Wanye Hu, Xu Wang, Jiayu Hu, Chen Yuan, Chaoting Zhou, Hairui Wang, Jing Du, Ying Wang*, Xiangmin Tong. TEOA Promotes Autophagic Cell Death via ROS-Mediated Inhibition of mTOR/p70S6k Signaling Pathway in Pancreatic Cancer Cells. Front Cell Dev Biol. 2021 Oct 6;9:734818. (通讯作者, SCI, IF=6.081)
12. Wanye Hu#, Chaoting Zhou#, Qiangan Jing#, Yancun Li, Jing Yang, Chen Yang, Luyang Wang, Jiayu Hu, Huanjuan Li, Hairui Wang, Chen Yuan, Yi Zhou, Xueying Ren, Xiangmin Tong*, Jing Du* and Ying Wang*. FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis. Cancer Cell International. 2021,21:709. (通讯作者, SCI, IF=5.722)
13. Yunqi Zhu, Xiangmin Tong, Ying Wang, Xiaoya Lu*. WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia. Cell Death Dis, 2021 Dec20; 13(1):18. (第三作者, SCI, IF=8.469)
14. Jingjing Zhang, Xingxing Xu, Huitao Liu, Lingting Jin, Xiya Shen, Changnan Xie, Weiwei Xiang, Danlu Yang, Wenjin Feng, Jiaojiao Wang, Mianxian Wang, Tianyingying Dong, Haoyu Qiu, Lihao Wu, Ying Wang*, Xu Zhang*, Zhihui Huang*. Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis. Cell Death Dis. 2021 Oct 5;12(10):907. (通讯作者, SCI, IF=9.685)
15. Jiayu Hu, Wanye Hu, Lusheng Tang, Ying Wang*. Fundamental neurocircuit of anti-inflammatory effect by electroacupuncture stimulation identified. Neurosci.Bull. 2022 Apr 18. doi: 10.1007/s12264-022-00849-2. Online ahead of print. (通讯作者, SCI, IF=5.203)
16. Jinghua Wu, Xu Wang, Mingqi Zhou, Guobo Chen, Jing Du, Ying Wang*, Chengyin Ye. The value of lymphocyte-to-monocyte ratio and neutrophil-to-lymphocyte ratio in differentiating pneumonia from upper respiratory tract infection (URTI) in children: a cross-sectional study. BMC Pediatrics, 2021,21:545. (通讯作者, SCI, IF=2.125)
17. XueyingRen, YanchunLi, YiZhou, WanyeHu, ChenYang, Qiangan Jing, Chaoting Zhou, Xu Wang, Jiayu Hu, Luyang Wang, Jing Yang, Hairui Wang, Haifeng Xu, Huanjuan Li, Xiangmin Tong*, Ying Wang*, Jing Du*. Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis. Redox Biology, Volume 46, October 2021, 102122. (SCI, IF=11.799). (通讯作者)
18. Jing Du#, Xu Wang#, Yanchun Li#, Xueying Ren, Yi Zhou, Wanye Hu, Chaoting Zhou, Qiangan Jing, Chen Yang, Luyang Wang, Huanjuan Li, Lijuan Fang, Yonglie Zhou*, Xiangmin Tong*, Ying Wang*. DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism. Cell Death Dis. 2021 Jul 15;12(7):705. (通讯作者, SCI, IF=8.469)
19. Yanchun Li#, Xin Wang #, Zhihui Huang #, Yi Zhou, Jun Xia, Wanye Hu, Xu Wang, Jing Du*, Xiangmin Tong*, Ying Wang*. CISD3 inhibition drives cystine-deprivation induced ferroptosis. Cell Death Dis. 2021 Sep 8;12(9):839. (通讯作者, SCI, IF=8.469)
20. Xingxing Xu, Xiya Shen, Jiaojiao Wang, Wenjin Feng, Mianxian Wang, Xuemeng Miao, Qian Wu, Lihao Wu, Xiaoning Wang, Yimin Ma, Shuang Wu, Xiaomei Bao, Wei Wang, Ying Wang*, Zhihui Huang*. YAP prevents premature senescence of astrocytes and cognitive decline of Alzheimer's disease through regulating CDK6 signaling. Aging Cell. 2021 Aug 20;e13465. (通讯作者, SCI, IF=9.304)
21. Mengxian Jia, Wenbin Zhang, Junle Zhu, Changgang Huang, Jian Zhou, Jiashu Lian, Ying Wang*, Honglin Teng* and Zhihui Huang*. Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients. Frontiers in oncology, 2021. Aug 4;11:685893. (通讯作者, SCI, IF=6.244)
22. Qian Wu, Xuemeng Miao, Jingjing Zhang, Ludan Xiang, Xiuchun Li, Xiaomei Bao, Siyu Du, Mianxian Wang, Shuangda Miao, Yiren Fan, Wei Wang, Xingxing Xu, Xiya Shen, Danlu Yang, Xiwu Wang, Yuanyuan Fang, Lixin Hu, Xuyi Pan, Haoru Dong, Hui Wang, Ying Wang*, Jia Li*, Zhihui Huang*. Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling. Theranostics, 11(17):8480-8499, 2021. (通讯作者, SCI, IF=11.556)
23. Jin Yu, Yannan Wang, Yi Wu, Sisi Lin, Rui Hao, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Hui Huang, Feifei Zhou, Ying Wang*. Pharmacokinetics of Meloxicam Tablets in Healthy Chinese Adults in the Fasting and Fed States: A Single-Site, Single-Dose, Randomized, Open, 2-Period, 2-Sequence, Crossover Bioequivalence Study. Clin Pharmacol Drug Dev. 2021 Jun 17. doi: 10.1002/cpdd.965. Online ahead of print. (SCI, IF=2.448). (通讯作者)
24. Wu Yi, Peiyuan Yan, Sisi Lin, Rui Hao, Yannan Wang, Jin Yu, Lu Fang, Jingjing Zhu, Di Zhao, Shengjia Tong, Yongkai Si, Tiantian Ye, Zeyu Wu, Zhiquan Qin, Hua Huang, Chongyang Deng, Jingchao Sun, Ying Wang*. Pharmacokinetics and Safety of a Single Dose and Multiple Doses of Allisartan Isoproxil, an Angiotensin II Receptor Blocker, in Healthy Chinese People. Clin Pharmacol Drug Dev. 2021 July 8. doi: 10.1002/cpdd.995. Online ahead of print. (SCI, IF=2.448). (通讯作者)
25. Jing Du#, Yi Zhou#, Yanchun Li#, Jun Xia, Yongjian Chen, Sufeng Chen, Xin Wang, Weidong Sun, Tongtong Wang, Xueying Ren, Xu Wang, Yihan An, Kang Lu, Wanye Hu, Siyuan Huang, Jianghui Li, Xiangmin Tong*,Ying Wang*. Identification of Frataxin as a regulator of ferroptosis, Redox Biology, 2020 May;32:101483. (SCI, IF=11.799). (通讯作者)
26. Huitao Liu#, Jingjing Zhang#, Xingxing Xu#, Sheng Lu, Danlu Yang, Changnan Xie, Mengxian Jia, Wenbin Zhang, Lingting Jin, Xiwu Wang, Xiya Shen, Fayi Li, Wangfei Wang, Xiaomei Bao, Sijia Li, Minyu Zhu, Wei Wang, Ying Wang*, Zhihui Huang*, Honglin Teng*, SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury through NF-kB signaling, Theranostics, 11(9):4187-4206, 2021. (通讯作者, SCI, IF=11.556)
27. Danlu Yang#; Xingxing Xu#; Xin Wang; Wenjin Feng; Xiya Shen; Jingjing Zhang; Huitao Liu; Changnan Xie; Qian Wu; Xuemeng Miao; Yifan Guo; Hao Cai; Lihao Wu; Shuxian Zhou; Xinfei Yao; Ying Wang*; Tian Xie*; Zhihui Huang*; β-elemene promotes the senescence of glioma cells through regulating YAP-CDK6 signaling, American Journal of Cancer Research, 2021,11(2):370-388. (通讯作者, SCI, IF=6.166)
28. Tongtong Wang#, Jing Du#, Dexia Kong#, Guosheng Yang, Qihao Zhou, Fei You, Yan Lin *, Ying Wang*. Gambogic acid inhibits proliferation and induces apoptosis of human acute T‑cell leukemia cells by inducing autophagy and downregulating β‑catenin signaling pathway: Mechanisms underlying the effect of Gambogic acid on T‑ALL cells. ONCOLOGY REPORTS, 2020 Oct;44(4):1747-1757. (SCI, IF=3.906). (通讯作者)
29. Tongtong Wang#, Yannan Wang#, Sisi Lin, Lu Fang, Sai Lou, Di Zhao, Jingjing Zhu, Qigang Yang, Ying Wang*. Evaluation of pharmacokinetics and safety with bioequivalence of Amlodipine in healthy Chinese volunteers: Bioequivalence Study Findings. J Clin Lab Anal. 2020 Jun;34(6):e23228. (通讯作者) (SCI, IF=2.352).
30. Xingxing Yu#, Xin Wang#, Xu Wang#, Yi Zhou, Yanchun Li, Aiwei Wang, Tongtong Wang, Yihan An, Weidong Sun, Jing Du*, Xiangmin Tong* and Ying Wang*. TEOA Inhibits Proliferation and Induces DNA Damage of Diffuse Large B-Cell Lymphoma Cells Through Activation of the ROS-Dependent p38 MAPK Signaling Pathway. Front Pharmacol. 2020 Sep 4;11:554736. (通讯作者) (SCI, IF=5.81).
31. Kang Lu, Sisi Lin, Yannan Wang, Rui Hao, Lu Fang, Jingjing Zhu, Di Zhao, Jin Yu, Shengjia Tong, Yi Wu, Yongkai Si, Tiantian Ye, Qigang Yang, Ying Wang*. Pharmacokinetics and Safety of Fosaprepitant Dimeglumine in Healthy Chinese Volunteers: Bioequivalence Study. Clin Pharmacol Drug Dev. 2021 Jul;10(7):748-755. doi: 10.1002/cpdd.892. (通讯作者)（SCI，IF=2.448）.
32. Xingxing Xu#, Xiya Shen#, Wenjin Feng#, Danlu Yang, Jingjing Zhang, Jiaojiao Wang, Mianxian Wang, Zhang Ting, Chaobo Meng, Roumeng Chen, Xinru Zheng, Leilei Du, Lina Xuan, Ying Wang*, Tian Xie*, Zhihui Huang*. D-galactose induced glioblastoma senescence through YAP-CDK6 pathways. Aging-US, 2020, 12(18):18501-18521. (SCI, IF=5.68).
33. Changnan Xie#, Xiya Shen#, Xingxing Xu#, Huitao Liu, Fayi Li, Sheng Lu, Ziran Gao, Jingjing Zhang, Qian Wu, Danlu Yang, Xiaomei Bao, Fan Zhang, Shiyang Wu, Zhaoting lv, Minyu Zhu, Dingjun Xu, Peng Wang, Wei Wang, Zengqiang Yuan, Ying Wang, Honglin Teng*, Zhihui Huang*. Astrocytic YAP promotes formation of glia scars and neural regeneration after spinal cord injury, Journal of Neuroscience, 2020 Mar 25;40(13):2644-2662. (SCI, IF=5.62).
34. Xiaomei Bao#, Xingxing Xu#, Qian Wu#, Jingjing Zhang, Danlu Yang, Fayi Li, Sheng Lu, Huitao Liu, Zhaoting Lv, Zhang Fan, Xiya Shen, Changnan Xie, Shiyang Wu, Wei Wang, Ying Wang*, Honglin Teng*, Zhihui Huang*. Sphingosine 1-phosphate promotes the proliferation of olfactory ensheathing cells through YAP signaling and participates in the formation of olfactory nerve layer. Glia, 2020 Sep;68(9):1757-1774. doi: 10.1002/glia.23803. (SCI, IF=7.452). (通讯作者).
35. Xiya Shen#, Xingxing Xu#, Changnan Xie#, Huitao Liu, Danlu Yang, Jingjing Zhang, Qian Wu, Ling Wang, Leilei Du, Lina Xuan, Chaobo Meng, Haitao Zhang, Wei Wang, Ying Wang*, Tian Xie*, Zhihui Huang*. YAP promotes the proliferation of neuroblastoma cells through decreasing the nuclear location of p27Kip1 mediated by Akt. Cell Proliferation, 2020, 53:e12734. (SCI, IF=6.831). (通讯作者)
36. Zhihui Huang, Ying Wang#. In vivo electroporation and time-lapse imaging of the rostral migratory stream in developing rodent brain. Current Protocols in Neuroscience, 2019 Apr;87(1):e65. doi: 10.1002/cpns.65. (通讯作者)（Book Chatper）
37. Jing Du*, Tongtong Wang*, Yanchun Li*, Yi Zhou, Xin Wang, Xingxing Yu, Xueying Ren, Yihan An, Yi Wu, Weidong Sun, Weimin Fan, Qiaojuan Zhu, Ying Wang#, Xiangmin Tong#. DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin. Free Radical Biology and Medicine, 2019 (131): 356-369. (SCI, IF=6.02). (通讯作者)
38. Ying Wang*, Jian-liang Tang, Xingxing Xu, Xin-ping Zhou, Jing Du, Xin Wang, Yi Zhou, Qiaojuan Zhu, Ling-ling Yao, Yong-gang Wang*, Shuangxing Hou*, Zhihui Huang*. NMDA receptors inhibit axonal outgrowth by inactivating Akt and acticating GSK-3β via calcineurin in cultured immature hippocampal neurons. Experimental Cell Research. 2018. 371: 389-398. (SCI, IF=3.329). (通讯作者)
39. Ying Wang, Xiaomei Bao, Shiyang Wu, Xiya Shen, Fan Zhang, Zhaoting Lv, Qian Wu, Changnan Xie, Huitao Liu, Jian Lin*, Honglin Teng*, Zhihui Huang*. Semaphorin 3A as an inhibitive factor for migration of olfactory ensheathing cells through cofilin activation is involved in formation of olfactory nerve layer. Molecular and Cellular Neuroscience. 2018 Oct;92:27-39. (SCI, IF=3.182). (Faculty 1000 Recommendations, Very Good, By Bernd Fritzsch, University of Iowa, USA )
40. Jing Du*, Ying Wang*, Yan-chun Li, Tong-tong Wang, Yong-lie Zhou, Zhen-hua Ying. Acute diffuse alveolar hawmorrhage accompanied by gastrointestinal bleeding in a patient with serious systemic lupus erythematosus: a case report. Journal of International Medical Research, 2018, 46(5): 2046-2053. (SCI, IF=1.351).
41. Yu Chen, Tongtong Wang, Jing Du, Yanchun Li, Xin Wang, Yi Zhou, Xingxing Yu, Weimin Fan, Xiangmin Tong*, Ying Wang*. The Critical Role of PTEN/PI3K/AKT Signaling Pathway in Shikonin-Induced Apoptosis and Proliferation Inhibition of Chronic Myeloid Leukemia. Cell Physiol Biochem 2018; 47(3):981–993. (SCI, IF=5.01). (通讯作者)
42. Junyu Zhang, WeiE Liu, Jing Du, Yangjin Jin, Minlei Zhao, Linjie Li, Ying Wang*. Prognostic impact of miR-196a/b expression in adult acute myeloid leukaemia: a single-centre, retrospective cohort study. Journal of International Medical Research, 2018, 46(9): 3675-3683. (SCI, IF=1.351). (通讯作者)
43. Hangxing Bao, Jing Du, Bingyu Chen and Ying Wang*. The role of thromboelastography in predicting hemorrhage risk in patients with leukemia. Medicine (Baltimore). 2018 Mar; 97(13):e0137. (SCI, IF=1.87). (通讯作者)
44. Yiwei Xie, Zhaoyun Li, Jing Du, Yu Chen, Bing-yu Chen, Tongtong Wang, Zhihui Huang, Shuangxing Hou, Ying Wang*. Visualization of rostral migratory stream in the developing rat brain by in vivo electroporation. Cellular and Molecular Neurobiology. 2018, 38: 1067–1079. (SCI, IF=3.811). (通讯作者)
45. Cheng-gen Zheng, Fan Zhang, Xiao-mei Bao, Shi-yang Wu, Peng Wang, Jia-nan Zhou, Yuan Gao, Hong-lin Teng, Ying Wang*，Zhi-hui Huang*. Polarized Distribution of Active Myosin II Regulates Directional Migration of Cultured Olfactory Ensheathing Cells. Scientific Reports. 2017 July; 7-4701. (SCI, IF=4.122) . (通讯作者)
46. Hangxing Bao, Peijian Tong, Caixia Li, Jing Du, Bingyu Chen, Zhihui Huang, Ying Wang*. Efficacy of fresh packed red blood transfusion in organophosphate poisoning. Medicine (Baltimore). 2017 Mar; 96(11):e6375. (SCI, IF=2.028). (通讯作者)
47. Ying Wang, Binyu Chen, Zhen Wang, Wei Zhang, Ke Hao, Yu Chen, Kaiqiang Li, Tongtong Wang, Yiwei Xie, Zhihui Huang, Xiangmin Tong*. Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement. Oncotarget. 2016 Dec 13;7(50): 82851-82863. doi: 10.18632/oncotarget.12654. (SCI, IF=5.08).
48. Ying Wang, Hong-lin Teng, Yuan Gao, Fan Zhang, Yu-Qiang Ding*, Zhihui Huang*. Brain-derived Neurotrophic Factor Promotes the Migration of Olfactory Ensheathing Cells through TRPC Channels. Glia. 2016 Dec; 64(12):2154-2165. (SCI, IF=6.03).
【荣誉与奖励】省部级以上
人才项目
1. 获得浙江省自然科学基金杰出青年基金
2. 入选2019年度浙江省级人才
3. 入选2018年度浙江省卫生创新人才
4. 入选2017年度浙江省151人才工程第三层次
5. 入选2014年度温州市551人才工程第三层次
科研奖项
1. 第二十三届中国专利奖优秀奖，2022，一种微量透析器及透析装置，王莹，杜璟，李艳纯，童向民。中国专利奖优秀奖。
2. 2020年浙江省科技进步二等奖：恶性血液病新型诊疗体系和预后模型的建立及应用。童向民，王莹，王世兵，许秋然，倪万茂，杜璟，陈一瑞。浙江省人民政府。
3. 2018年浙江省科技进步二等奖：脊髓损伤修复的基础和临床研究。王莹，黄智慧，滕红林，周婧，徐跻峰，王元姣，温学花，王俊娟，宋法寰。浙江省人民政府。
4. 2018年浙江省医药卫生科技一等奖：脊髓损伤修复的基础和临床研究。王莹，黄智慧，滕红林，周婧，徐跻峰，温学花，王俊娟，宋法寰。浙江省卫生计生委。
5. 2019年浙江省科技进步三等奖：再生微环境在脊髓损伤修复的基础和临床研究。黄智慧，滕红林，王莹，张旭，李佳，张纯武，王宇。浙江省人民政府。
6. 2016年浙江省医药卫生科技二等奖：Slits/Robos系统在外周雪旺细胞髓鞘化中的作用及其机制。黄智慧，王莹，孔晓霞，陈然，申屠杨萍，陈兆琴，王凤，薛峰。浙江省卫生计生委。
7. 2015年温州市科学技术进步奖三等奖：王莹，黄智慧，滕红林。Slits/Robos-RhoA系统在胶质细胞髓鞘化和形态可塑性中的分子机制。温州市人民政府。
8. 2015年温州市永乐科技奖励医疗救助基金会医药科技成果奖三等奖：Slits/Robos-RhoA系统在胶质细胞形态可塑性和迁移中作用及分子机制，黄智慧，王莹，滕红林。温州市永乐科技奖励医疗救助基金会
9. 2012年浙江省自然科学学术奖二等奖：黄智慧，王莹，苏志达，耿建国，Slit-2通过钙依赖的Cofilin 激活和RhoA的抑制排斥嗅鞘细胞迁移。
【授权专利及转化】
成果专利
1. A method for extraxting anti-tumor compounds from Actinidia eriantha Benth. Root, Australia Innovation Patent. 王莹，童向民，张琳，（2020104046，已授权）
2. Anti-virus transmission type medical waste bin with negative pressure function. Australia Innovation Patent. 王莹，周怡，童向民， (2021103618，已授权)
3. Microdialyzer and dialysis apparatus. Australia Innovation Patent. 王莹，杜璟，李艳纯，童向民， (2021101907，已授权)
4. 一种含有乌骨藤提取物的药物组合物，国家发明专利。王莹，童向民，陈秉宇，王震，（ZL 2017 1 0048478.5，已授权）
5. 一种在活体动物脑内利用电穿孔辅助基因转移标记神经元的方法，国家发明专利。（201510038228.4，已受理，实审中）
6. 一种微量透析器及透析装置，国家发明专利，王莹，杜璟，李艳纯，童向民，（ZL 2018 1 0982578.X，已授权）。
7. YAP抑制剂在制备抗肿瘤药物中的应用，国家发明专利。黄智慧，王莹，滕红林，陈毕，（ZL 2015 1 0101046.7，已授权，第二）
8. 用于悬浮细胞快速换液的分隔式滤网，国家实用新型专利，王莹，杜璟，童向民，（ZL 201720772768.X，已授权）。
9. 升级型悬浮细胞快速换液的分隔式滤网，国家实用新型专利，杜璟，王莹，童向民，（ZL 2017 2 1809647.4，已授权）。
10. 用于离心机快速平衡的比对尺，，王莹，童向民，范卫敏，国家实用新型专利（ZL 2018 2 0076857.5，已授权）。
11. 一种用于粘稠半固体试剂转移的大口径移液枪头，王莹，童向民，范卫敏，国家实用新型专利（ZL 2019 2 0651632.2，已授权）。
12. 一种防滑手柄肥皂，国家实用新型专利，王莹，童向民，范卫敏，（ZL 2019 2 0651617.8,已授权）。
13. 一种用于引流胸水的胸腔引流管，国家实用新型专利，王燕南，王莹，张望刚，（ZL 2019 2 0651261.8，已授权）。
14. 一种具有负压功能的防病毒传染型医疗垃圾桶，王莹，周怡，童向民，国家实用新型专利（ZL 2020 2 0438366.8，已授权）。
15. 一种充气式带压力表的压脉带，国家实用新型专利，王莹，童向民，逯康，朱利芬，（ZL 2020 2 0704750.8，已授权）。
16. 一种负压吸引式穿刺引流装置，国家实用新型专利，童向民，周怡，王莹，（ZL 2020 2 0932650.0，已授权）。
17. 一种利用D-半乳糖制备神经胶质瘤细胞衰老模型的方法，国家发明专利，黄智慧，徐星星，沈细亚，谢恬，王莹，冯文金，（ZL 2019 1 0876446.3，已授权）。
18. 一种可视回血Y型采血针，国家实用新型专利，庾瑾，王莹，童向民，（ZL202121037314.0，已授权）。
19. 一种药房专用常温药品分类储藏柜，国家实用新型专利，郝睿，王莹，童向民，（ZL 2021 2 0550884.3，已授权）。